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The G6PD (Glucose-6-Phosphate Dehydrogenase) test is a blood test that checks the activity level of the G6PD enzyme in red blood cells. This enzyme plays a vital role in protecting red blood cells from damage caused by oxidative stress.
A deficiency in G6PD can lead to hemolytic anemia, especially after exposure to certain drugs, infections, or foods like fava beans. It is a genetic condition, more common in males, and may be inherited from one or both parents. The test is particularly important before starting certain medications (e.g., antimalarials, sulfa drugs) or in patients with unexplained anemia or jaundice.