DUAL MARKER Detail

The Dual Marker Test is a non-invasive first-trimester prenatal screening test used to assess the risk of chromosomal abnormalities in a developing fetus, particularly Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and Patau syndrome (Trisomy 13).

This blood test measures levels of two biochemical markers:

• Free Beta-human Chorionic Gonadotropin (Free β-hCG)

• Pregnancy-Associated Plasma Protein A (PAPP-A)

Abnormal levels of these markers can indicate a higher risk of chromosomal defects. The test is usually done between 9 and 13 weeks of gestation, and the results are interpreted in combination with nuchal translucency (NT) scan findings, maternal age, and gestational age.

The Dual Marker test is not diagnostic, but it helps identify pregnancies at higher risk and determines whether further testing like NIPT or invasive procedures (CVS or amniocentesis) may be needed.

It is a safe and effective early screening tool for expectant mothers and forms a key component of antenatal care.