KARYOTYPING-BLOOD Detail

Karyotyping - Blood is a laboratory test that analyzes the number and structure of chromosomes in peripheral blood lymphocytes. It involves culturing white blood cells, arresting them in metaphase, staining, and then examining them under a microscope to create a karyogram. This test is used to identify chromosomal abnormalities such as aneuploidies (e.g., Down syndrome), translocations, deletions, duplications, or inversions.

It is commonly recommended in cases of:

• Congenital abnormalities

• Developmental delays

• Recurrent pregnancy loss

• Infertility investigations

• Suspected genetic syndromes

• Prenatal diagnosis (in specific cases)

Results from karyotyping can help in diagnosing genetic disorders, counseling affected families, and guiding treatment or reproductive decisions.