HBsAg-ELISA Detail

The HBsAg ELISA test is an enzyme-linked immunosorbent assay used to detect the presence of Hepatitis B surface antigen (HBsAg) in the blood. HBsAg is the earliest indicator of acute or chronic Hepatitis B virus (HBV) infection.

A positive HBsAg result means:

• The person is currently infected with HBV

• They may be in the acute or chronic phase of infection

• The individual is infectious and can transmit the virus to others

This test is:

• Routinely used in HBV screening programs

• Essential in blood donor screening

• Recommended during pregnancy to prevent mother-to-child transmission

• Used to monitor recovery or persistence of infection in HBV patients

If HBsAg remains positive for more than 6 months, it indicates chronic Hepatitis B infection.

This test is usually ordered alongside:

• Anti-HBs (Hepatitis B surface antibody)

• HBeAg and Anti-HBe

• HBV DNA levels for full assessment