HBeAG-ELISA Detail

The HBeAg ELISA test is an enzyme-linked immunosorbent assay (ELISA) used to detect the presence of Hepatitis B e Antigen (HBeAg) in the blood. HBeAg is a secreted viral protein associated with the active replication of the Hepatitis B Virus (HBV) and is considered a marker of high viral infectivity.

A positive HBeAg result suggests:

• Active HBV replication

• The individual is highly infectious

• A possible increased risk of liver damage, such as chronic hepatitis or cirrhosis

This test is commonly used:

• To monitor disease activity in chronic HBV infection

• In Hepatitis B screening panels along with HBsAg, Anti-HBs, and Anti-HBe

• During pregnancy to assess the risk of mother-to-child transmission

• To guide antiviral treatment decisions and assess treatment response

A negative HBeAg with positive anti-HBe may indicate reduced infectivity or a transition to the inactive carrier state.